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What is inorganic chemical industry, what are the inorganic chemical industry？
Inorganic chemical industry is the abbreviation of inorganic chemical industry. It uses natural resources and industrial by-products as raw materials to produce inorganic acids such as sulfuric acid, nitric acid, hydrochloric acid, and phosphoric acid, soda ash, caustic soda, synthetic ammonia, chemical fertilizers, and inorganic salt. The main raw materials of inorganic chemical products are sulfur, sodium, phosphorus, potassium, calcium and other chemical minerals and coal, oil, natural gas, air, water and so on. In addition, by-products and wastes in many industrial sectors are also raw materials for inorganic chemicals, such as: coke oven gas in the coking production process in the iron and steel industry. The ammonia contained in it can be recovered by sulfuric acid to make ammonium sulfate. Sulfur dioxide in the smelting exhaust gas of lead ore and sphalerite can be used to produce sulfuric acid. The inorganic chemical industry includes sulfuric acid industry, soda ash industry, chlor-alkali industry, synthetic ammonia industry, chemical fertilizer industry and inorganic salt industry. In a broad sense, it also includes the production of inorganic non-metallic materials and fine inorganic chemicals such as ceramics and inorganic pigments.
Inorganic chemical industry is a basic raw material-material industrial product with wide application and large demand. Its uses involve the paper industry, rubber, plastics, pesticides, feed additives, trace element fertilizers, space technology, mining, oil extraction, navigation, high-tech fields in the information industry, electronics industry, and various material industries, as well as people in daily life Clothing, food, housing, transportation, light industry, environmental protection, and transportation are closely related.
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What are the uses of basic organic chemical products?
The use of basic organic chemical products can be summarized in three main areas:
① The raw materials for the production of synthetic rubber, synthetic fibers, plastics and other high-molecular chemical products, that is, monomers for polymerization;
②Other organic chemical industries, including raw materials for fine chemical products;
③According to the properties of the product, it is used for certain direct consumption, for example, used as a solvent, refrigerant, antifreeze, heat carrier, gas absorbent, and anesthetic and disinfectant used directly in medicine.
It can be seen from the above that the importance of basic organic chemical industry is the basis for the development of various organic chemical production and the main component of the modern industrial structure.
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What are the common pharmaceutical intermediates?
What are the common pharmaceutical intermediates? Pharmaceutical intermediates refer to chemical raw materials or chemical products used in the pharmaceutical synthesis process. From the perspective of the development history of China's pharmaceutical intermediate industry, after nearly 30 years of development, pharmaceutical intermediates have evolved from a small branch of the chemical industry into an emerging industry with billions of dollars in output value, and their market competition has become increasingly fierce. The following editors will introduce you to several common pharmaceutical intermediates:
N-benzyl-N-methylethanolamine
N-benzyl-N-methylethanolamine is an important pharmaceutical intermediate that can synthesize anti-asthma and anti-allergy drugs, antihypertensive drug nicardipine and some new drugs for the treatment of cardiovascular diseases; in addition, it can also synthesize pesticide herbicides and plants Fungicides and metal preservatives.
Methyl 4,4’-dimethoxyacetoacetate
Methyl 4,4’-dimethoxyacetoacetate is an important intermediate for the treatment of cardiovascular and cerebrovascular diseases, Nilvadipine, and is currently the leading therapeutic drug for cardiovascular and cerebrovascular diseases in the international market. Glyoxylic acid is used as the raw material to synthesize trimethyl orthoformate in the presence of concentrated sulfuric acid to obtain methyl dimethoxyacetate. ester.
α-methylene cyclic ketone
Alpha-methylene cyclic ketone is the active center of many drugs with anti-cancer activity, which contains α, β-unsaturated ketone structure, which is a hidden group of anti-cancer active groups, and has become an important synthesis of many important cyclic anti-cancer drugs Intermediate.
4-propylthio-o-phenylenediamine
4-Propylthio-o-phenylenediamine is a key intermediate of the highly effective broad-spectrum deworming drug albendazole. Albendazole is a new drug marketed in the late 1980s. Imidazole drugs have the strongest medicinal properties.
Pazopanib
Pazopanib is a new oral angiogenesis inhibitor developed by GlaxoSmithKline that can interfere with the neovascularization required for the survival and growth of stubborn tumors, targeting vascular endothelial growth factor receptor (VEGFR), It works by inhibiting the formation of new blood vessels that supply blood to tumors. It is suitable for the treatment of advanced renal cell carcinoma (a type of kidney cancer in which cancer cells are found in renal tubules), soft tissue sarcoma (STS), epithelial ovarian cancer, and non-small cell lung cancer (NSCLC).
2,4-dichloro-5-methoxyaniline
Bosutinib, developed by Wyeth Pharmaceuticals, was approved by the EU in September 2010 as an "orphan drug" for the treatment of chronic myeloid leukemia (CML). On September 4, 2012, the drug was approved for marketing by the US Food and Drug Administration (FDA) under the brand name Bosulif. The European Food and Drug Administration (EMA) endorsed the market on March 27, 2013, and the PMDA endorsement on the market in Japan on September 26, 2014.
